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    Health Related
    Side Effects of Sickle Cell

1. Anemia (trouble with the blood carrying oxygen)
2. Severe pain and swelling in hands, feet and joints
3. Exhaustion and tiring due to anemia
4. Jaundice (a yellowish discoloration of the whites of the eyes)
5. Leg ulcers may occur around the ankles. They usually appear after puberty and are difficult to heal
6. Delayed onset of puberty and growth retardation in both sexes are common problems
7. Strokes may occur
8. Nose bleeds may be a problem
9. Frequency of urination can be expressed by bedwetting, which is most common among children with sickle cell anemia
10. Gallstones are common occurrence in adolescents and adults
11. Kidney infections
12. Destruction of parts of bones
13. Disturbance in vision (usually blurring)
14. Enlargement of spleen or heart
15. Heart murmurs frequently occur
16. Hand-foot syndrome (swollen hand and feet in children)
17. Pneumonia
18. Poor appetite
19. Difficulties during pregnancy
20. Major body organs may be affected (i.e. heart, lungs, kidney, brain, abdomen, spleen, eyes and liver)